- Genetic epidemiology sites
- Other twin research groups
- External data repositories
Out researchers have developed a range of statistical analysis packages, software programmes and visualisation tools to facilitate genetic research.
Visualisation of regional epigenome-wide association scan (EWAS) results and DNA co-methylation patterns.
Power of variance component multipoint linkage analysis studies through simulations.
Author: Mario Falchi (DTR) and Cesare Cappio Borlino (Shardna)
An open resource for phenotype-expression associations and interactive exploration of GxE effects on gene expression.
Genetic epidemiology sites
Below you will find useful genetic epidemiology websites with resources for genetic researchers and for data analysis, including structural modelling and genotypic data.
Mx is a matrix algebra interpreter and numerical optimiser for structural equation modelling and other types of statistical modelling of data.
Founded in 1974, The Society is an international nonprofit, multidisciplinary organisation focusing on genetic research, in particular twin research. They host an annual conference called the International Congress on Twin Studies.
Other twin research groups
TwinsUK is not the only twin research group. Below is a list of some of the other major twin cohorts around the world, some of which have been established for many years.
Set up in the 1950s, the Danish Twin Registry is one of the longest standing registries in the world. The registry has been expanded to include information on almost all twins born in Denmark since the 1870s.
Established in 1987, the Netherlands Twin Registry started as a birth cohort following the development of sets of twins from birth. The registry now has over 87,000 twins and multiples of all ages, with 175,000 members in total including parents, siblings and spouses.
The Swedish Twin Registry was established in the 1960s and holds information from around 85,000 identical and non-identical twin pairs. Research covers topics such as allergies, cancer, dementia and cardiovascular disease.
This is Australia’s only national twin research centre of excellence, based at the University of Melbourne. The registry comprises over 70,000 twins which represents nearly 20 percent of Australia’s entire twin population.
QTwin was set up in 2006. It is a population-based registry of identical and non-identical twins of all ages, living in Australia.
External data repositories
On this page you will find a list of sites that hold TwinsUK data that are free to access.
A repository of 3D images of faces automatically landmarked in 4249 facial points. Four curvature descriptors were computed on all landmarks to create phenotypic traits.
This site, an EMBL-EBI repository, hosts multiple TwinsUK gene expression and methylation datasets. These datasets are completely freely available.
The Gene Expression Omnibus holds multiple TwinsUK gene expression and methylation datasets. These datasets are completely freely available.
The European Genome-phenome Archive holds TwinsUK gene expression, methylation and whole genome sequence data. These data are under managed access. The TwinsUK governing committee TREC must approve access to these data. Please visit our access our data pages for further information.