Study Reveals ZOE Personalised Diets Yield Health Improvements 

9th May 2024 – by Aaruthy Suthahar

In a recent study published in the scientific journal Nature Medicine, researchers from ZOE, who are running the largest in-depth nutrition study in the world, examined the impact of personalised dietary advice versus general recommendations on cardiometabolic health. This study, involving 347 participants aged 41 to 70 years, sheds light on the effectiveness of tailored dietary programmes. 

Participants were randomly assigned to either receive personalised dietary guidance by ZOE or standard care advice based on the US Department of Agriculture Guidelines for Americans. The personalised dietary programme utilised various factors including food characteristics, individual responses to food, microbiomes, and health history to create personalised food scores over an 18-week period. 

Results showed a significant reduction in triglyceride levels, which are types of fat in the blood, among participants following the personalised dietary programme compared to those receiving standard advice. However, there were no significant changes in low-density lipoprotein cholesterol. Additionally, improvements were noted in other measures such as body weight, waist circumference, HbA1c levels (which is a measure of blood sugar over time), diet quality, and the variety of gut bacteria, particularly among participants who closely followed the personalised programme. 

It is noteworthy that participants following the ZOE programme reported feeling better, with improvements in mood, reduced hunger, better sleep, and increased energy compared to the control group. Those who closely adhered to the ZOE advice also experienced greater improvements in weight and increases in diet quality, associated with lower risk for heart disease and diabetes. 

Overall, the study shows the potential benefits of personalised dietary advice in improving cardiometabolic health outcomes, providing valuable insights for individuals seeking effective dietary interventions. TwinsUK members were instrumental in enabling ZOE to develop their personalised dietary programme through the original research study on personalised diets, PREDICT.  

Recent Blog Post

New Study Reveals Epigenetic Markers for Type 2 Diabetes Complications in Identical Twins 

23rd April 2024 – by Aaruthy Suthahar A recent collaborative effort among seven international twin cohorts, including TwinsUK, has yielded...

Celebrating International Women's Day: Stories from Twins and TwinsUK Staff

25th March 2024 – by Aaruthy Suthahar International Women’s Day (IWD) on March 8th is a day to celebrate the...

TwinsUK part of team awarded £20 million to study bowel cancer

7th March 2024 – by TwinsUK and King’s College London TwinsUK will receive part of £20m in funding by Cancer...