At TwinsUK, our research spans a diverse range of themes, all aimed at understanding the factors that influence human health and ageing. From exploring the role of genetics and omics in disease, to studying the microbiome, nutrition, and resilience in ageing, our work provides valuable insights into how we can improve health outcomes. We also contribute to large-scale initiatives such as the UK Longitudinal Linkage Collaboration (UK LLC) and play a key role in COVID-19 research. Each of these themes builds on over 30 years of data from our dedicated twin volunteers.