Approved Requests

Approved Requests

This page provides a record of the data access applications that have been reviewed and approved by the TwinsUK Resource Executive Committee. Each request listed below has been evaluated in line with our data governance policies, ethical standards, and our overall aim to promote and contribute to further scientific research and generate new ideas and knowledge.

 

For all enquiries regarding data access submissions, please email: victoria.vazquez@kcl.ac.uk

Project Title
APPROVAL DATE
REFERENCE
Exploring the Therapeutic Roles in Alzheimer's Disease and Ageing: Interactions between the NAD+-mitophagy axis and Circadian Rhythms, RNA dysregulation and neuronal death.
05/02/2025
E1319
Analysis of the relationship between gut microbiota and irritable bowel syndrome
06/05/2026
E1411
Epigenetic Mechanisms Underlying APOL1-Associated Chronic Kidney Disease in the TWINS Cohort
06/05/2026
I1408
Microbiome-wide genome association study with serum triglyceride levels
15/04/2026
E1400
Harmonizing large-scale human phenome datasets to transform data silos into connected resources for interoperability
15/04/2026
E1398
DynaMAP pilot
04/03/2026
I1391
Modelling Longitudinal Lung Function Trajectories in the TwinsUK Cohort to Predict Asthma and COPD
04/02/2026
I1394
DOPA-Kiss
04/02/2026
E1392
MASCAREIGNE
14/01/2026
E1387
Decoding Epigenetic Disease Signatures in Twins Discordant for Systemic Lupus Erythematosus
05/11/2025
E1371
Unlocking comprehensive cardiovascular health insights with advanced wearable data
03/09/2025
E1361
Epidemiological scale analysis of somatic mutation landscapes in the germline
07/05/2025
E1315
Metabolites associated with Genus Blautia
12/03/2025
I1334
Characterizing de-novo SV formation from long read sequencing of human sperm
12/03/2025
E1333
Relating senescence to clinical resilience and environmental and nutritional factors
12/03/2025
I1335
Developing multiomics signatures of frailty through systems biology and machine learning in a deeply phenotyped wellness cohort
19/02/2025
E1311
Prediction of Events from Wearables
12/03/2025
I1334
Sexual Dimorphism in Human Muscle Ageing
12/03/2025
I1332
Co-evolution between humans and their gut microbiota
05/02/2025
E1323
Dichotic Digits Testing in Twins UK
12/02/2025
I1326
Ageing profiles and influential factors for abnormal ageing - MR imaging study twins
05/02/2025
I1330
Lateral Dexa scan to quantify abdominal aortic calcification
12/02/2025
I1327
Mediation of resilience differences between discordant twins by serum factors and mitochondrial bioenergetics
02/04/2025
E1338
Investigating the Impact of Extrinsic Factors on Clonal Haematopoiesis and Cardiovascular Disease Outcomes in the TwinsUK Cohort
02/04/2025
I1327
The role of sociodemographic factors in attendance at cancer and cardiovascular disease screening and in emergency cancer diagnosis before, during and after the COVID-19 pandemic in people with severe or complex mental illness
09/04/2025
E1340

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