Our goal is to understand how genetic variation relates to human health and disease and genetics underlies almost all research at the DTR. We have collected genetic information on over 6,000 twins (both monozygotic and dizygotic) using both state of the art genotyping (Illumina platform) and whole genome sequencing (WGS) techniques.
We have collaborated with international research groups to identify genes causing the most common, and sometimes lethal, conditions, such as cardiovascular disease, diabetes, obesity, fractures, and osteoarthritis.